Melatonina
Anno: 2012
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Riferimento:J Pineal Res. 2012 Jan;52(1):12-20.Azione della melatonina:Mlt (1mM) could stimulate the differentiation of preadipocytes (3T3-L1) into adipocytes.Target:3T3-L1 adipocytes.
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Riferimento:J Pineal Res. 2012 Jun 27.Azione della melatonina:DNA methylation patterns induced by melatonin (1nm) suggest a potential mechanism of the anticancer effect in melatonin-treated breast cancer cells.Target:DNA methylation
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Riferimento:Am J Epidemiol. 2012 Nov 1;176(9):751-9.Azione della melatonina:Night work may increase cancer risk at several sites among men, possibly via suppression of melatonin release.Target:Night work.
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Riferimento:J Appl Toxicol. 2012 Dec;32(12):952-8.Azione della melatonina:Study on disruption of circadian rhythmicity in humans (children if possible) under long-term exposure to weak ELF MF.Target:Extremely low-frequency (ELF) magnetic fields (MF)
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Riferimento:J Pineal Res. 2012 Apr;52(3):322-31.Azione della melatonina:Melatonin sensitizes human hepatoma cells to ER tress-induced apoptosis by down-regulating COX-2 xpression, incresing the levels of CHOP and decreaing the Bcl-2/Bax ratio.Target:Endoplasmin reticulum, Cyclooxygenase-2, Pro-apoptotic transcription factor.
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Riferimento:Recent Pat Anticancer Drug Discov. 2012 Sep;7(3):337-44.Azione della melatonina:Systemic effects of darkness and excessive melatonin synthesis enables cancer protection treatment for people living in light-deficient environment.Target:Racial/ethnic disparities
Anno: 2013
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Riferimento:BMC Cell Biol. 2013 Jan 7;14:1.Azione della melatonina:Melatonin enhance DNA repair capacity by affecting several key genes involved in DNA damage responsive pathways.Target:DNA repair capacity
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Riferimento:Breast Cancer Res Treat. 2013 Feb;137(3):677-87.Azione della melatonina:Melatonin or a melatonin receptor agonist may be useful biologic additions in the treatment of some forms of triple negative human breast carcinoma.Target:TNBC