Melatonina
Anno: 2012
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Riferimento:BMJ Open. 2012 Jan 11;2(1).Azione della melatonina:The effect of melatonin in a breast cancer population with the above-mentioned indications has not yet been studied.Target:Clock-gene, PER3.
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Riferimento:Neuro Endocrinol Lett. 2012 Dec 28;33(8).Azione della melatonina:Observational study on 55 patients affected lymphoma, treated with the Di Bella Method (DBM). The 1, 3 and 5-year survival rates are reported, together with any signs of toxicity. The patients were able to continue the treatment at home, carrying out their normal activities without problems.Target:Di Bella Method (DBM).
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Titolo: Melatonin suppresses aromatase expression and activity in breast cancer associated fibroblastsRiferimento:Breast Cancer Res Treat. 2012 Apr;132(2):765-71.Azione della melatonina:MLT inhibits estrogen production in breast adipose fibroblasts (BAFs) by inhibiting transcription of the CYP19A1 gene.Target:Physiological doses of MLT.
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Riferimento:J Recept Signal Transduct Res. 2012 Dec;32(6):290-7.Azione della melatonina:EMR increase the risk of breast cancer suppressing the production of melatonin which may modulate breast cancer through enhanced oxidative stress and Ca(2+) influx in cell lines.Target:Electromagnetic radiation (EMR)
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Titolo: Melatonin interferes in the desmoplastic reaction in breast cancer by regulating cytokine productionRiferimento:J Pineal Res. 2012 Apr;52(3):282-90.Azione della melatonina:One millimolar melatonin induced a reduction in TNF-α, IL-6, and IL-11 mRNA expression in MCF-7 and 3T3-L1 cells.Target:Aromatase enzyme,tumor necrosis factor (TNF)-α, interleukin (IL)-11 and interleukin (IL)-6.
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Riferimento:Sleep Med Rev. 2012 Nov 5.Azione della melatonina:Melatonin suppression increased breast cancer risk, in night and rotating female shift workers.Target:Shift work
Anno: 2013
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Riferimento:BMC Cell Biol. 2013 Jan 7;14:1.Azione della melatonina:Melatonin enhance DNA repair capacity by affecting several key genes involved in DNA damage responsive pathways.Target:DNA repair capacity
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Riferimento:Breast Cancer Res Treat. 2013 Feb;137(3):677-87.Azione della melatonina:Melatonin or a melatonin receptor agonist may be useful biologic additions in the treatment of some forms of triple negative human breast carcinoma.Target:TNBC