Melatonina
Anno: 1995
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Riferimento:Oncol Rep. 1995 Sep;2(5):871-3.Azione della melatonina:Association of MLT(20 mg/day orally) may make TMX effective also in ER-negative metastatic breast cancer patients.Target:Tamoxifen (TMX) Melatonin(MLT) Estrogen receptor (ER)
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Riferimento:Cancer Lett. 1995 Jul 13;93(2):207-12.Azione della melatonina:Direct relation between proliferative rate of cells and melatonin (10(-9)M) actions on MCF-7 cells.Target:Inhibitory actions on cell growth
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Riferimento:Oncology. 1995 Jul-Aug;52(4):278-83.Azione della melatonina:Clear stimulation of the immune system and Mlt at early but inhibition at advanced stages of cancer.Target:Mlt and cellular immunity
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Riferimento:Br J Cancer. 1995 Apr;71(4):854-6.Azione della melatonina:Concomitant administration of MLT (os,20mg/day) may induce tumour regressions in metastatic breast cancer patients refractory to TMX alone.Target:Melatonin (MLT) Tamoxifen (TMX)
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Titolo: The nuclear receptor for melatonin represses 5-lipoxygenase gene expression in human B lymphocytesRiferimento:J Biol Chem. 1995 Mar 31;270(13):7037-40.Azione della melatonina:5-lipoxygenase is the natural RZR alpha responding gene.New perspective in the involvement of MLT in inflammatory and immunological reactions.Target:Retinoid Z receptor (RZR alpha and beta)
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Riferimento:Breast Cancer Res Treat. 1995 Mar;33(3):257-64.Azione della melatonina:Melatonin/ovarian-steroid contraceptive will restore the lost mechanism of endogenous anovulation.Target:Seasonal ovulation
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Riferimento:J Pineal Res. 1995 Mar;18(2):93-103.Azione della melatonina:Melatonin (10(-9) M) induces growth inhibition in breast tumor cells.Target:Estrogen receptor (ER)
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Riferimento:Med Hypotheses. 1995 Jan;44(1):39-46.Azione della melatonina:Mindfulness meditation is associated with increased physiological levels of melatonin.Target:Effect of meditation on 6-sulphatoxymelatonin
Anno: 1996
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Riferimento:Toxic Rep Ser. 1996 Sep;58:1-B6.Azione della melatonina:Magnetic field exposure, cause of leukemia and other cancers, was not associated with a significant reduction in serum melatonin.Target:Electric and magnetic fields.
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Riferimento:Br J Cancer. 1996 Nov;74(9):1466-8.Azione della melatonina:Combination with Tamoxifene plus Melatonin (20 mg day) may have some benefit in untreatable metastatic solid tumour patients.Target:Melatonin/tamoxifen