Neoplasie della mammella
Anno: 2006
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Titolo: Inhibitory effects of melatonin on the growth of pituitary prolactin-secreting tumor in ratsRiferimento:J Pineal Res. 2006 Apr;40(3):230-5.Azione della melatonina:Melatonin (0.125, 0.25, 0.50 or 1.0 mg melatonin/ day/rat subcutaneously at 17:30-18:00 hr.) inhibits the proliferation and induces apoptosis of rat pituitary prolactin-secreting tumor via perturbation of mitochondria physiology.Target:Beta-estradiol (E2) (prolactinoma)
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Titolo: Cancer and rhythmRiferimento:Cancer Causes Control. 2006 May;17(4):483-7.Azione della melatonina:No abstract available.Target:No abstract available.
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Riferimento:Ann Epidemiol. 2006 Aug;16(8):622-31.Azione della melatonina:Exposure to magnetic fields is associated with decressed nocturnalmelatonin levels, but does not support the hypothesis that such exposure results in increased urinary levels of estrogens, LH, or FSH.Target:Electromagnetic fields ((EMF))
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Titolo: Antiestrogens modulate MT1 melatonin receptor expression in breast and ovariancancer cell linesRiferimento:Oncol Rep. 2006 Jan;15(1):231-5.Azione della melatonina:Data suggest that melatonin signaling is modulated by antiestrogens in breast and ovarian cancer cells.Target:MT1 melatonin receptor.
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Riferimento:Int J Biol Markers. 2006 Oct-Dec;21(4):242-5.Azione della melatonina:Our data suggest that storage temperatures might affect degradation of aMT6s during storage.Target:6-sulfatoxymelatonin (aMT6s).
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Riferimento:Cancer Detect Prev. 2006;30(2):118-28.Azione della melatonina:Melatonin oncostatic actions on hormone-dependent mammary tumors are mainly based on its antiestrogenic actions, also by regulating the activity of the aromatases.Target:Estrogen-signaling pathways.
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Riferimento:J Pineal Res. 2006 Mar;40(2):116-24.Azione della melatonina:Age, reproductive and menopausal factors, body mass index (BMI), alcohol consumption, smoking history, night shift work were significantly related to lower levels of melatonin, whereas parity was significantly associated with higher aMT6s levels.Target:6-sulfatoxymelatonin (aMT6s)
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Riferimento:Epidemiology. 2006 Jan;17(1):108-11.Azione della melatonina:Results suggest a modestly elevated risk of breast cancer after longer periods of rotating night work.Target:Shift work.
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Riferimento:Vopr Onkol. 2006;52(5):491-8.Azione della melatonina:No abstract available.Target:No abstract available.
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Riferimento:J Am Assoc Lab Anim Sci. 2006 May;45(3):38-44.Azione della melatonina:Melatonin (MLT), eicosapentaenoic acid (EPA), and conjugated linoleic acid (CLA) inhibit growth and metabolism in several rodent and human tumors, to suppress tumor uptake of linoleic acid (LA).Target:MLT, EPA, CLA, LA.