Neoplasie della mammella
Anno: 2006
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Riferimento:Cancer Detect Prev. 2006;30(2):118-28.Azione della melatonina:Melatonin oncostatic actions on hormone-dependent mammary tumors are mainly based on its antiestrogenic actions, also by regulating the activity of the aromatases.Target:Estrogen-signaling pathways.
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Riferimento:J Pineal Res. 2006 Mar;40(2):116-24.Azione della melatonina:Age, reproductive and menopausal factors, body mass index (BMI), alcohol consumption, smoking history, night shift work were significantly related to lower levels of melatonin, whereas parity was significantly associated with higher aMT6s levels.Target:6-sulfatoxymelatonin (aMT6s)
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Riferimento:Vopr Onkol. 2006;52(5):491-8.Azione della melatonina:No abstract available.Target:No abstract available.
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Riferimento:J Am Assoc Lab Anim Sci. 2006 May;45(3):38-44.Azione della melatonina:Melatonin (MLT), eicosapentaenoic acid (EPA), and conjugated linoleic acid (CLA) inhibit growth and metabolism in several rodent and human tumors, to suppress tumor uptake of linoleic acid (LA).Target:MLT, EPA, CLA, LA.
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Riferimento:J Pineal Res. 2006 May;40(4):291-6.Azione della melatonina:In vivo, Cd mimics the effect of estrogens in the uterus and mammary gland. Melatonin is a specific inhibitor of Cd-induced ER alpha-mediated transcription.Target:ER alpha and ER beta.
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Titolo: Circulating tumoral cells lack circadian-rhythm in hospitalized metastasic breast cancer patientsRiferimento:Clin Transl Oncol. 2006 Nov;8(11):826-9.Azione della melatonina:Increased breast tumorigenesis has been reported in melatonin-suppressed experimental models.Target:Circulating Tumor Cells (CTC) circadian- rhythm.
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Riferimento:Cancer Causes Control. 2006 May;17(4):573-6.Azione della melatonina:Melatonin may decrease risk of hormone-related cancers or even act as a potent antioxidant and thus have a protective effect against cancer development.Target:LAN
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Riferimento:Indian J Med Sci. 2006 Dec;60(12):523-35.Azione della melatonina:The exposure to light at night (LAN) and anthropogenic electric and magnetic fields (EMFs) is related to the increased incidence of breast cancer and childhood leukaemia via melatonin disruption.Target:LAN and EMFs.
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Riferimento:Cancer Causes Control. 2006 May;17(4):559-71.Azione della melatonina:Due to the suppression of melatonin by light it can be assumed that too much artificial light at night could be responsible for generally increasing rates of breast cancer in industrialized countries.Target:LAN, shift work.
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Riferimento:Cancer Causes Control. 2006 May;17(4):553-8.Azione della melatonina:Magnetic field exposures suppress melatonin production and that melatonin is protective against breast cancer.Target:Electromagnetic fields. (EMF)