Neoplasie della mammella
Anno: 2007
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Riferimento:Scand J Work Environ Health. 2007 Oct;33(5):336-43.Azione della melatonina:No evidence was found for an association between shift work and breast or prostate cancer, or all cancer sites combined among shift workers.Target:Nighttime shift workers.
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Riferimento:Prof Inferm. 2007 Apr-Jun;60(2):89-93.Azione della melatonina:Nurses who attend night shifts should undergo strict and periodical breast cancer screening, since the risk is significantly increased in this population.Target:Light-at-night
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Riferimento:Mol Cell Biochem. 2007 Jan;294(1-2):19-24.Azione della melatonina:Intense exercise-induced stress enhances mammary carcinogenesis through the involvement of adrenaline and prolactin, also confirmed a role of melatonin as a therapeutic aid against breast cancer in general.Target:"Anti-stress" role of Mlt.
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Riferimento:Complement Ther Clin Pract. 2007 Aug;13(3):137-45.Azione della melatonina:Baseline salivary cortisol and melatonin were not significantly correlated with STAI scores and did not change significantly following reflexology.These findings will be transferred to a study involving breast cancer patients where effects display disregulation of cortisol and melatonin secretion.Target:Self-reported anxiety (STAI)
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Riferimento:Breast Cancer Res Treat. 2007 Jul;103(3):331-41.Azione della melatonina:Melatonin and estrogen in BCF predicted growth inhibition and stimulation. Biological monitoring of BCF may help identify women with GCBD at greatest risk for breast cancer development.Target:(GCBD) Gross cystic breast disease Breast cyst fluid (BCF).
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Riferimento:Crit Rev Oncog. 2007 Dec;13(4):303-28Azione della melatonina:Both human epidemiological and experimental studies on animals have documented that a potential negative consequence of chronodisruption and nocturnal melatonin inhibition is cancer initiation and growth (breast, prostate, endometrial, and colorectal).Target:LAN
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Riferimento:Cell Cycle. 2007 Jun 1;6(11):1329-31.Azione della melatonina:Here we speculate on the molecular pathways that may couple the circadian machinery to breast cancer.Target:Circadian clock
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Riferimento:J Pineal Res. 2007 Apr;42(4):403-10.Azione della melatonina:Female mice were treated with CdCl(2) (2-3 mg/kg, i.p.), melatonin (10 microg/mL in drinking water), CdCl(2) + melatonin, or diluents. The effects of Cd are partially inhibited by melatonin.Target:Cd-induced carcinogenicity.
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Riferimento:Sleep Med. 2007 Sep;8(6):613-22.Azione della melatonina:Female shiftworkers compared to non-shiftworkers are more likely to report menstrual irregularity and longer menstrual cycles.Target:Circadian disruption.
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Riferimento:Oncol Rep. 2007 Apr;17(4):947-53.Azione della melatonina:Melatonin inhibits both aromatase activity as a selective estrogen enzyme modulator. 20% at 1 nM; 40% at 10 microM Mlt concentrations.Target:MT1 melatonin receptor.