Neoplasie della mammella

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Anno: 2008

  • Titolo: An indomethacin analogue...
    Riferimento:
    Biochem Pharmacol. 2008 Jan 15;75(2):484-93.
    Azione della melatonina:
    Identification of CBM as a specific inhibitor of AKR1C3 and the resultant effects on prostate and breast cancer cells.
    Target:
    N-(4-chlorobenzoyl)- melatonin (CBM)
  • Titolo: Melatonin as a selective estrogen enzyme modulator
    Riferimento:
    Curr Cancer Drug Targets. 2008 Dec;8(8):691-702.
    Azione della melatonina:
    Melatonin inhibits the growth of breast cancer by interacting with estrogen-signaling(SERM)-(SEEM) pathways.
    Target:
    Selective estrogen recetor modulator (SERM), selective estrogen enzyme modulator (SEEM).
  • Titolo: Suppression of implanted MDA-MB 231 human breast cancer growth in nude mice by dietary walnut
    Riferimento:
    Nutr Cancer. 2008;60(5):666-74.
    Azione della melatonina:
    Tumor cell proliferation was decreased, but apoptosis was not altered due to walnut consumption.
    Target:
    Walnuts diet.
  • Titolo: [Sleep medicine in occupational health]
    Riferimento:
    G Ital Med Lav Ergon. 2008 Jul-Sep;30(3):276-9.
    Azione della melatonina:
    Shift-work has been associated with breast cancer, due to a circadian disruption and to a nocturnal suppression in melatonin production.
    Target:
    Shift-work.
  • Titolo: Melatonin and estradiol effects on food intake, body weight, and leptin in ovariectomized rats
    Riferimento:
    Maturitas. 2007 Sep 20;58(1):91-101.
    Azione della melatonina:
    In ovariectomized rats,melatonin reduced food intake and partially prevented the increase of body weight and cholesterol, without changing leptin levels.
    Target:
    Sulphatoxymelatonin (aMT6s).
  • Titolo: Sleep duration and the risk of breast cancer: the Ohsaki Cohort Study
    Riferimento:
    Br J Cancer. 2008 Nov 4;99(9):1502-5.
    Azione della melatonina:
    In a prospective study on Japanese women, short sleep duration was associated with higher risk of breast cancer.
    Target:
    LAN
  • Titolo: Melatonin, environmental light, and breast cancer
    Riferimento:
    Breast Cancer Res Treat. 2008 Apr;108(3):339-50.
    Azione della melatonina:
    Melatonin,at physiological concentration,suppresses estrogen receptor(ER) gene, modulates several estrogen dependent regulatory proteins and pro-oncogenes, inhibits cell proliferation, and impairs the metastatic capacity of MCF-7 human breast cancer cells.
    Target:
    Estrogen receptor (ER)

Anno: 2009

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