Neoplasie della mammella
Anno: 2009
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Riferimento:J Pineal Res. 2009 Jan;46(1):115-6.Azione della melatonina:No abstract available.Target:No abstract available.
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Riferimento:Cancer Causes Control. 2009 Nov;20(9):1753-6.Azione della melatonina:Blind women withNPL(no perception of light)appear to have a lower risk of breast cancer, compared to blind women with LP. Mechanisms influenced by melatonin or circadian synchronization.Target:Blindness.
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Riferimento:Chem Biol Interact. 2009 Mar 16;178(1-3):221-7.Azione della melatonina:N(4-chlorobenzoyl)melatonin as a specific AKR1C3 inhibitor validate its role in the proliferation of breast cancer cells.Target:Aldo-keto reductase (AKR) 1C3
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Riferimento:J Pineal Res. 2009 May;46(4):422-32.Azione della melatonina:Expression of MT1 and coexpression of MT1/ nestin in invading tumor cells in more advanced tumors suggest an important role for GPCR in pathogenesis of breast cancer.Target:G-protein-coupled receptor (GPCR).
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Riferimento:Free Radic Biol Med. 2009 Jan 15;46(2):253-62.Azione della melatonina:NQO2 is a newly discovered binding site (MT3) of melatonin, indicating that it could be a novel target for prevention of breast cancer initiation.Target:Quinone oxidoreductase 2 (NQO2).
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Riferimento:J Pineal Res. 2009 Aug;47(1):23-31.Azione della melatonina:Treatment of MCF-7 breast cancer cells with melatonin counteracted the increase induced by estradiol almost completely.Target:Membrane-bound receptor MT1.
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Riferimento:Breast Cancer Res Treat. 2009 Nov;118(2):293-305.Azione della melatonina:Amplification of the MT1gene in some breast tumors and an inverse correlation with ERalpha, PR and MT1 G protein-coupled melatonin receptor.Target:Estrogen receptor alpha (Eralpha), progesterone receptor (PR).
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Riferimento:Anticancer Agents Med Chem. 2009 Jun;9(5):500-16.Azione della melatonina:We should seriously consider alternative mechanisms such as melatonin or retinoic acid,that may be beneficial to patients' well being.Target:Increasing survival and patients' quality of life.
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Riferimento:Breast Cancer Res Treat. 2009 Jun;115(3):437-52.Azione della melatonina:Use of antioxidant supplements (vit C, vit E, multivitamins, glutamine, glutathione, melatonin) during chemotherapy, radiation therapy, and/or hormonal therapy for breast cancer.Target:Antioxidant supplements.
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Riferimento:Mutat Res. 2009 Nov-Dec;680(1-2):106-8.Azione della melatonina:Light-at-night exposure can induce deleterious epi-genetic changes in Per3 (5-VNTR)-(4-VNTR) genes.Target:Mlt/LAN