[A case of rectal carcinoid with multiple liver, lymph nodes and bone metastases that respon

Gan To Kagaku Ryoho. 2010 Nov;37(12):2349-51.
Yamashita K1, Takase S, Nakamura T, Matsuda Y, Imanishi T, Sumi Y, Suzuki S, Kamigaki T, Ku Y, Kuroda D.
Gan To Kagaku Ryoho. 2010 Nov;37(12):2349-51.
Effetto di octreotide LAR su un carcinoide rettale, con molteplici tumori epatici metastatici, ha portato a un buon controllo dei sintomi e una inibizione della crescita tumorale a lungo termine.
Octreotide LAR/carcinoide rettale.

A 45-year-old man was admitted to our hospital with a chief complaint of anal bleeding. Colonoscopy revealed a lower rectal tumor diagnosed as rectal carcinoid on biopsy. Multiple metastatic liver tumors were found on abdominal CT scan. We performed an abdomino-perineal resection, a partial hepatectomy, and TACE. There seemed to be no apparent residues of a carcinoid tumor on abdominal CT. About one year after the first therapy, CT scan had revealed multiple metastases to the liver, lymph nodes and bones. Therefore, we started an octreotide LAR, which remarkably reduced the size of metastatic tumors. The treatment of an octreotide LAR had controlled the progression of metastatic tumors for two and half years. In this case, the effect of an octreotide LAR for recurrence of rectal carcinoid after local therapies brought good controls of symptoms and an inhibition of tumor growth for long-term.