The use of retinoids in ovarian cancer: a review of the literature

Riferimento: 
Int J Gynecol Cancer. 2012 Feb;22(2):191-8.
Autori: 
Whitworth JM, Straughn JM Jr, Atigadda VR, Muccio DD, Buchsbaum DJ. Jenny.Whitworth@obgyn.uab.edu
Fonte: 
Int J Gynecol Cancer. 2012 Feb;22(2):191-8.
Anno: 
2012
Azione: 
I retinoidi, una classe di composti contenenti vitamina A, i suoi derivati naturali e gli analoghi sintetici, sono stati studiati estesamente sia nella prevenzione che nel trattamento delle neoplasie ginecologiche.
Target: 
Retinoidi/neoplasie ginecologiche.

Abstract
Ovarian cancer is the deadliest of all gynecologic malignancies. The search for novel treatment modalities to augment traditional chemotherapy and improve quality of life is ongoing. Retinoids, a class of compounds composed of vitamin A, its natural derivatives, and synthetic analogs, have been studied extensively in both the prevention and treatment of gynecologic malignancies. In this article, we reviewed preclinical studies and clinical trials conducted using retinoids in ovarian cancer.

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