Advances in the chemoprevention of non-melanoma skin cancer in high-risk organ transplant recipients

Riferimento: 
Semin Oncol. 2012 Apr;39(2):134-8.
Autori: 
Lien MH, Fenske NA, Glass LF. mlien@health.usf.edu
Fonte: 
Semin Oncol. 2012 Apr;39(2):134-8.
Anno: 
2012
Azione: 
Efficacia degli agenti retinoidi orali nella chemioprofilassi dei carcinomi a cellule squamose (SCC) in alto rischio di tumori della pelle.
Target: 
Retinoidi orali/carcinoma a cellule squamose.

ABSTRACT
Patients with a history of more than four basal cell carcinomas (BCCs) or squamous cell carcinomas (SCCs) are at high risk for developing further skin cancers. Immunosuppressed patients, especially solid organ transplantation patients, harbor a higher risk of developing SCC. Systemic retinoids have been demonstrated to possess chemoprophylactic properties in the treatment of non-melanoma skin cancer. This article reviews the efficacies of the available oral retinoid agents in the chemoprophylaxis of SCCs in high-risk solid organ transplant recipients.

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