Leucemie Linfomi Mielomi

Leucemie Linfomi Mielomi

Extremely low frequency electromagnetic fields as effectors of cellular responses in vitro: possible immune cell activation

J Cell Biochem. 2004 Sep 1;93(1):83-92.
Simkó M, Mattsson MO.
Electromagnetic field (EMF) and extremely low frequency (ELF) exposure is able to perform such activation by means of increasing levels of free radicals, causing an inhibition of the effects of the melatonin.
DNA damage.

Oxidative DNA damage induced by a melatonin metabolite, 6-hydroxymelatonin, via a unique non-o-quinone type of redox cycle

Biochem Pharmacol. 2004 Nov 1;68(9):1869-78.
Sakano K, Oikawa S, Hiraku Y, Kawanishi S.
6-Hydroxymelatonin induced site-specific DNA damage in the presence of Cu(II). Damaged G and C of the 5'-ACG-3' sequence complementary to codon 273 of the p53 gene.
Oxidative DNA damage by its metabolite.

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