Leucemie Linfomi Mielomi
Anno: 2012
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Riferimento:J Pineal Res. 2012 Apr;52(3):322-31.Azione della melatonina:Melatonin sensitizes human hepatoma cells to ER tress-induced apoptosis by down-regulating COX-2 xpression, incresing the levels of CHOP and decreaing the Bcl-2/Bax ratio.Target:Endoplasmin reticulum, Cyclooxygenase-2, Pro-apoptotic transcription factor.
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Riferimento:Dig Dis Sci. 2012 Oct 10.Azione della melatonina:Supplementation by exogenous melatonin (20 and 40 mg/kg body weight) significantly reduces MTX-induced small intestinal damage.Target:Methotrexate (MTX).