Melatonina
Anno: 1999
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Riferimento:Neuro Oncol. 1999 Jul;1(3):212-20.Azione della melatonina:Reasonable support for a causal role of EMF on brain cancer.Target:General review.
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Titolo: Does winter darkness in the Artic protect against cancer? The melatonin hypothesis revisitedRiferimento:Med Hypotheses. 1999 Jul;53(1):1-5.Azione della melatonina:Research on a melatonin-inhibited carcinogenesis in the low-risk populations of the Arctic should be pursued.Target:Melatonin hypothesis.
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Riferimento:Bioelectromagnetics. 1999 Sep;20(6):338-46.Azione della melatonina:Explanation for the observed ornithine decarboxylase (ODC) changes after magnetic fields (MF) exposure is the melatonin hypothesis.Target:50 Hz magnetic fields.
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Riferimento:Life Sci. 1999;65(4):415-20.Azione della melatonina:Melatonin (1 nM) inhibits MCF-7 cell proliferation with an increased expression of p21WAF1 protein mediated by the p53 pathway.Target:p53/p21WAF1.
Anno: 2000
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Riferimento:Anticancer Res. 2000 May-Jun;20(3B):2103-5.Azione della melatonina:The concomitant administration of low-dose IL-2 plus Mlt may prolong the survival time in untreatable advanced hematologic malignancies.Target:Low doses of Interleukin-2 (IL-2).
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Riferimento:Exp Toxicol Pathol. 2000 May;52(2):93-101.Azione della melatonina:The role of melatonin in human mammary cancer are discussed.Target:Tumor transplants and depression of melatonin.
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Riferimento:Breast Cancer Res Treat. 2000 Dec;64(3):287-96.Azione della melatonina:Melatonin can be produced by an organ or tissue other than the pineal gland.Target:LAN
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Titolo: Melatonin and climacteryRiferimento:Med Sci Monit. 2000 Nov-Dec;6(6):1209-12. Review.Azione della melatonina:Melatonin has the potential to markedly delay the appearance of palpable mammary tumors, combination with flaxseed oil caused a significant decrease in the number/weight of tumors.Target:Delay/prevent breast cancer.
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Riferimento:J Pineal Res. 2000 May;28(4):210-8.Azione della melatonina:The growth-inhibitory effects of melatonin are transduced through the membrane-associated G-protein coupled mt1 melatonin receptor.Target:Estrogen receptor (ER).
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Riferimento:Pathophysiology. 2000 Apr;7(1):47-51.Azione della melatonina:Essential participation of endogenous opioids in hormonal regulation, a response to stress caused by beginning chemotherapy.Target:Stress in the course of neoplastic diseases.