Melatonina
Anno: 1986
-
Riferimento:J Neural Transm Suppl. 1986;21:433-49.Azione della melatonina:Physiological concentrations of mlt has inhibitory effects on MCF-7 cancer cell growth in culture.Target:Mlt/estradiol/ prolactin
Anno: 1987
-
Titolo: Correlation between changes in prolactin and melatonin serum levels after radical mastectomyRiferimento:Tumori. 1987 Jun 30;73(3):263-7.Azione della melatonina:MLT serum values were significantly higher in patients than in controls. Radical mastectomy influences PRL and MLT secretions.Target:Prolactin (PRL) Melatonin (MLT)
-
Riferimento:Crit Rev Clin Lab Sci. 1987;25(3):231-53. Review.Azione della melatonina:Great decline in the elevated melatonin level of oncological patients following institution of chemotherapy.Target:Mlt induce mitotic arrest
-
Riferimento:Eur J Cancer Clin Oncol. 1987 Jul;23(7):949-57.Azione della melatonina:The oncological patients showed significantly higher mean melatonin serum levels than the control subjects. Mean melatonin values were lower in patients with solid tumours who had metastases, than in cases without metastases. GH and PRL serum levels were similar to control subjects.Target:MLT-GH-PRL.
-
Riferimento:Eur J Cancer Clin Oncol. 1987 Jul;23(7):949-57.Azione della melatonina:The oncological patients showed higher mean melatonin serum levels than the control subjects. Mlt values were lower in patients with solid tumours who had metastases. Chemotherapy caused a decre- ase. Surgery was followed by a fall in melatonin in patients without metastases.Target:Mlt/oncological patients
Anno: 1988
-
Riferimento:Med Hypotheses. 1988 Dec;27(4):303-11.Azione della melatonina:Hypothalamic-pituitary axis could be significant in the aetiology of breast cancer as high prolactin and melatonin levels may be protective.Target:Hypothyroidism
-
Riferimento:Cancer Res. 1988 Nov 1;48(21):6121-6.Azione della melatonina:Melatonin (10(-9) M; 10(-11) M) exerts a direct but reversible, antiproliferative effect on MCF-7 cell growth in culture.Target:Ultrastructural features
-
Riferimento:Cancer. 1988 Aug 1;62(3):494-9.Azione della melatonina:The beta-endorphin/melatonin ratio was higher than 2 in normal subjects and in cancer patients without metastases, whereas was lower than 2 in all patients with metastases.Target:Pineal and opioid system
-
Riferimento:Tumori. 1988 Jun 30;74(3):339-45.Azione della melatonina:Patients (75%) whose mlt enhanced after chemotherapy had an objective regression.Target:Mlt as a predictor
-
Riferimento:J Urol. 1988 May;139(5):1099-102.Azione della melatonina:MCF breast cancer tissue indicate an estrogen requirement for inhibition of growth by melatonin.Target:Inhibit tumor growth