Melatonina
Anno: 1993
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Riferimento:Eur J Cancer. 1993;29A(2):185-9.Azione della melatonina:Neuroimmunotherapy with low-dose IL-2 and MLT (50mg/day orally) is a biologically active and well tolerated strategy, capable of determining an apparent control of tumour growth in patients with advanced solid neoplasms.Target:Interleukin 2 (IL-2) plus .MLT
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Riferimento:Dtsch Med Wochenschr. 1983 Mar 25;108(12):470-4. Review.Azione della melatonina:No abstract available.Target:No abstract available.
Anno: 1994
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Riferimento:J Natl Cancer Inst. 1994 Jun 15;86(12):921-5.Azione della melatonina:Exposure to extremely low-frequency electromagnetic fields reduces the pineal gland's nocturnal production of the hormone melatonin.Target:Electric or magnetic fields.
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Riferimento:Br J Cancer. 1994 Jan;69(1):196-9.Azione della melatonina:The concomitant administration of MLT (40 mg day orally) may increase the efficacy of low-dose IL-2 subcutaneous therapy.Tumour objective regression rate was 11/41 vs 1/39, P < 0.001.Target:Interleukin 2 (IL-2) plus MLT.
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Titolo: Modulation of estrogen receptor mRNA expression by melatonin in MCF-7 human breast cancer cells.Riferimento:Mol Endocrinol. 1994 Dec;8(12):1681-90.Azione della melatonina:Antiproliferative actions of Mlt are mediated through the suppression of the transcription of ER gene.Target:Estrogen receptor (ER) mRNA
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Riferimento:Biol Signals. 1994 Nov-Dec;3(6):302-6.Azione della melatonina:Plasma melatonin concentrations in tumor-bearing rats killed at 3.00 h were suppressed by 35% when compared to the control animals killed at the same time.Target:Plasma melatonin concentrations
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Riferimento:Cancer Lett. 1994 Sep 30;85(1):105-9.Azione della melatonina:Antiproliferative effect was obtained by sequential exposure to 10(-9) M/10(-11)M 12/12h melatonin, which mimics the physiological rhythm of serum melatonin concentration.Target:Physiological rhythm/serum melatonin concentration
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Riferimento:J Pineal Res. 1994 Aug;17(1):25-32.Azione della melatonina:Melatonin(10(-9)M) may inhibit the action and/or release of growth stimulatory factors as well as stimulate the release of growth inhibitory factors.Target:Epidermal growth factor (EGF)
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Riferimento:J Natl Cancer Inst. 1994 Jun 15;86(12):921-5.Azione della melatonina:Exposure to extremely low-frequency electromagnetic fields reduces the production of melatonin.Target:ELF
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Riferimento:Ann N Y Acad Sci. 1994 May 31;719:502-25. Review.Azione della melatonina:No abstract available.Target:No abstract available.