Neoplasie della mammella

Target

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Azione della melatonina

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Anno: 1988

Titolo: Inhibition of Dunning tumor growth by melatonin

Riferimento:
J Urol. 1988 May;139(5):1099-102.

Azione della melatonina:
MCF breast cancer tissue indicate an estrogen requirement for inhibition of growth by melatonin.

Target:
Inhibit tumor growth
Titolo: Neuroimmunomodulation in cancer patients: correlations between melatonin and beta-endorphin blood levels and T helper/suppressor ratio

Riferimento:
Int J Biol Markers. 1988 Apr-Jun;3(2):82-6.

Azione della melatonina:
Metastatic patients had lower melatonin levels and a lower T4/T8 ratio.

Target:
MLT/ beta-endorphin

Anno: 1989

Titolo: The pineal gland and breast cancer: serum levels of melatonin in patients with mammary tumors and their relation to clinical characteristics

Riferimento:
Int J Biol Markers. 1989 Jul-Sep;4(3):157-62.

Azione della melatonina:
Melatonin concentrations were highest in breast cancer patients with the best prognosis.

Target:
Estrogen receptor-posit.
Titolo: Alterations of pineal gland and of T lymphocyte subsets in metastatic cancer patients: preliminary results

Riferimento:
J Biol Regul Homeost Agents. 1989 Oct-Dec;3(4):181-3.

Azione della melatonina:
Serum levels of MLT were higher in patients with low CD4/CD8 ratio than in normal ratio.

Target:
T helper/suppressor ratio (CD4/CD8)
Titolo: Melatonin and steroid-dependent carcinomas

Riferimento:
Andrologia. 1989 Sep-Oct;21(5):429-31.

Azione della melatonina:
Melatonin level was lower in patients with breast cancer as compared to controls.

Target:
MLT play a role in breast carcinoma
Titolo: Stage-dependent depression of melatonin in patients with primary breast cancer. Correlation with prolactin, thyroid stimulating hormone, and steroid receptors

Riferimento:
Cancer. 1989 Jul 15;64(2):426-33.

Azione della melatonina:
Direct involvement of melatonin in the growth control of breast cancer.

Target:
Progesterone/androgen receptors

Anno: 1990

Titolo: Melatonin and human cancer

Riferimento:
J Steroid Biochem Mol Biol. 1990 Dec 20;37(6):983-7.

Azione della melatonina:
Patients with advanced tumors showed serum MT levels significantly higher than controls.

Target:
Controversial data
Titolo: Effects of the pineal hormone melatonin on the anchorage-independent growth of human breast cancer cells (MCF-7) in a clonogenic culture system

Riferimento:
Cancer Lett. 1990 Apr 20;50(2):115-9.

Azione della melatonina:
Cellular attachment may modify the sensitivity of MCF-7 cells towards melatonin.

Target:
Anchorage-dependent
Titolo: 6-sulphatoxymelatonin production in breast cancer patients

Riferimento:
J Pineal Res. 1990;8(3):269-76.

Azione della melatonina:
Women with malignant tumors appeared to have lower concentrations of aMT6s.

Target:
6-sulphatoxymelatonin (aMT6s)
Titolo: Secular or circannual effects of placebo and melatonin on murine breast cancer?

Riferimento:
Prog Clin Biol Res. 1990;341A:31-40.

Azione della melatonina:
No abstract available.

Target:
No abstract available.

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