Neoplasie della mammella
Anno: 2006
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Riferimento:Cancer Causes Control. 2006 May;17(4):573-6.Azione della melatonina:Melatonin may decrease risk of hormone-related cancers or even act as a potent antioxidant and thus have a protective effect against cancer development.Target:LAN
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Riferimento:Indian J Med Sci. 2006 Dec;60(12):523-35.Azione della melatonina:The exposure to light at night (LAN) and anthropogenic electric and magnetic fields (EMFs) is related to the increased incidence of breast cancer and childhood leukaemia via melatonin disruption.Target:LAN and EMFs.
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Riferimento:Cancer Causes Control. 2006 May;17(4):559-71.Azione della melatonina:Due to the suppression of melatonin by light it can be assumed that too much artificial light at night could be responsible for generally increasing rates of breast cancer in industrialized countries.Target:LAN, shift work.
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Riferimento:Cancer Causes Control. 2006 May;17(4):553-8.Azione della melatonina:Magnetic field exposures suppress melatonin production and that melatonin is protective against breast cancer.Target:Electromagnetic fields. (EMF)
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Riferimento:Int J Cancer. 2006 Jan 15;118(2):274-8.Azione della melatonina:Melatonin could exert its antitumoral effects on hormone-dependent mammary tumors by inhibiting the aromatase activity of the tumoral tissue.Target:Aromatase inhibitor (aminoglutethimide)
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Riferimento:Cancer Causes Control. 2006 May;17(4):539-45.Azione della melatonina:Increased risk of breast cancer associated with indicators of exposure to light-at-night and night shift work and decreased nocturnal of 6-sulphatoxymelatonin associated with exposure to 60-Hz magnetic fields in the bedroom the same night.Target:Light-at-night, night shift work, 60-Hz magnetic fields.
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Riferimento:J Pineal Res. 2009 Jan;46(1):15-21Azione della melatonina:Melatonin(1nM) inhibits cancer cell invasion and metastasis formation via ROCK-regulated microfilament and microtubule organization,through increased expression of two cell surface adhesion proteins, E-cadherin and beta(1)-integrin.Target:Rho-associated proteinkinase (ROCK).
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Titolo: Risk of breast cancer after night- and shift work: current evidence and ongoing studies in DenmarkRiferimento:Cancer Causes Control 2006 May;17(4):531-7.
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Riferimento:J Sleep Res. 2006 Sep;15(3):241-9.Azione della melatonina:Little evidence that sleeping few hours per night was associated with breast cancer risk.Target:Circadian rhythms by melatonin.
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Titolo: Light during darkness and cancer: relationships in circadian photoreception and tumor biologyRiferimento:Cancer Causes Control. 2006 May;17(4):515-23.Azione della melatonina:The circadian rhythm for pineal melatonin secretion is regulated by the hypothalamic suprachiasmatic nucleus (SCN).Action spectra of melatonin suppression by light have shown that light in the 446-477 nm range,higher risk of breast cancer in industrialized countries is partly due to increased exposure to light at night.Target:LAN