Neoplasie della mammella
Anno: 2009
-
Titolo: Urinary melatonin levels and postmenopausal breast cancer risk in the Nurses' Health Study cohortRiferimento:Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):74-9.Azione della melatonina:An increased concentration of urinary aMT6s was associated with a lower risk of breast cancer.Target:6-sulfatoxymelatonin (aMT6s).
-
Titolo: Circadian clock manipulation for cancer prevention and control and the relief of cancer symptomsRiferimento:Integr Cancer Ther. 2009 Dec;8(4):387-97.Azione della melatonina:Single nucleotide polymorphisms within the genes of clock, clock-controlled, and melatonin pathways have been found to confer excess cancer risk or protection from cancer.Target:Per2 and Per1
-
Riferimento:Sleep Med Rev. 2009 Aug;13(4):257-64.Azione della melatonina:Studies suggest that a shortened duration of nocturnal sleep,circadian phase shifts, nocturnal melatonin suppression are associated with a higher risk of breast cancer development.Target:LAN
-
Riferimento:Postepy Hig Med Dosw (Online). 2009 Sep 15;63:425-34.Azione della melatonina:MT1 melatonin receptors benefits the efficacy of melatonin treatment.Target:MT1 (Mel1a) and MT2 (Mel1b) receptors.
-
Riferimento:Cancer Lett. 2009 Aug 18;281(1):1-7.Azione della melatonina:In breast cancer risk, melatonin may also block the estrogen receptor ERalpha and impact the enzyme aromatase, which produces estradiol.Target:Estrogen receptor Eralpha Enzyme aromatase.
-
Riferimento:J Pineal Res. 2009 Jan;46(1):115-6.Azione della melatonina:No abstract available.Target:No abstract available.
-
Riferimento:Br J Cancer. 2009 Nov 3;101(9):1613-9.Azione della melatonina:Melatonin(1nM)inhibits aromatase activity and expression by regulating the gene expression of specific aromatase promote region pI.4, and inhibit COX-2 and COX-1 mRNA expression.Target:COX-2/COX-1 mRNA expression.
-
Riferimento:Cancer Causes Control. 2009 Nov;20(9):1753-6.Azione della melatonina:Blind women withNPL(no perception of light)appear to have a lower risk of breast cancer, compared to blind women with LP. Mechanisms influenced by melatonin or circadian synchronization.Target:Blindness.
-
Riferimento:Chem Biol Interact. 2009 Mar 16;178(1-3):221-7.Azione della melatonina:N(4-chlorobenzoyl)melatonin as a specific AKR1C3 inhibitor validate its role in the proliferation of breast cancer cells.Target:Aldo-keto reductase (AKR) 1C3
-
Riferimento:J Pineal Res. 2009 May;46(4):422-32.Azione della melatonina:Expression of MT1 and coexpression of MT1/ nestin in invading tumor cells in more advanced tumors suggest an important role for GPCR in pathogenesis of breast cancer.Target:G-protein-coupled receptor (GPCR).