Neoplasie della mammella

Target

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Azione della melatonina

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Anno: 2012

Titolo: Genome-wide profiling in melatonin-exposed human breast cancer cell lines identifies differentially methylated genes involved in the anticancer effect of melatonin

Riferimento:
J Pineal Res. 2012 Jun 27.

Azione della melatonina:
DNA methylation patterns induced by melatonin (1nm) suggest a potential mechanism of the anticancer effect in melatonin-treated breast cancer cells.

Target:
DNA methylation
Titolo: A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis

Riferimento:
Eur J Cancer Prev. 2012 Mar;21(2):163-70.

Azione della melatonina:
Resveratrol in combination with melatonin has some protective effects on N-methyl-N-nitrosourea (NMU)-induced rodent breast cancer.

Target:
Chemoprevention with resveratrol and mlt.
Titolo: Health effects of extremely low-frequency magnetic fields: reconsidering the melatonin hypothesis in the light of current data on magnetoreception

Riferimento:
J Appl Toxicol. 2012 Dec;32(12):952-8.

Azione della melatonina:
Study on disruption of circadian rhythmicity in humans (children if possible) under long-term exposure to weak ELF MF.

Target:
Extremely low-frequency (ELF) magnetic fields (MF)
Titolo: Light deficiency confers breast cancer risk by endocrine disorders.

Riferimento:
Recent Pat Anticancer Drug Discov. 2012 Sep;7(3):337-44.

Azione della melatonina:
Systemic effects of darkness and excessive melatonin synthesis enables cancer protection treatment for people living in light-deficient environment.

Target:
Racial/ethnic disparities
Titolo: Melatonin promotes differentiation of 3T3-L1 fibroblasts

Riferimento:
J Pineal Res. 2012 Jan;52(1):12-20.

Azione della melatonina:
Mlt (1mM) could stimulate the differentiation of preadipocytes (3T3-L1) into adipocytes.

Target:
3T3-L1 adipocytes.
Titolo: Correlation of the risk of breast cancer and disruption of the circadian rhythm (Review)

Riferimento:
Oncol Rep. 2012 Aug;28(2):418-28.

Azione della melatonina:
Circadian system alteration and melatonin reduction, for exposure to light-at-night during night shift work, is the most valid hypotheses on the relation of shift work and breast cancer.

Target:
Night shift work
Titolo: Sleep duration, spot urinary 6-sulfatoxymelatonin levels and risk of breast cancer among Chinese women in Singapore

Riferimento:
Int J Cancer. 2012 May 30.

Azione della melatonina:
Sleep duration is not significantly associated with breast cancer risk reduction.

Target:
6-sulfatoxymelatonin (aMT6s)

Anno: 2013

Titolo: Melatonin enhances DNA repair capacity possibly by affecting genes involved in DNA damage responsive pathw

Riferimento:
BMC Cell Biol. 2013 Jan 7;14:1.

Azione della melatonina:
Melatonin enhance DNA repair capacity by affecting several key genes involved in DNA damage responsive pathways.

Target:
DNA repair capacity
Titolo: Expression of melatonin receptors in triple negative breast cancer (TNBC) in African American and Caucasian women: relation to survival

Riferimento:
Breast Cancer Res Treat. 2013 Feb;137(3):677-87.

Azione della melatonina:
Melatonin or a melatonin receptor agonist may be useful biologic additions in the treatment of some forms of triple negative human breast carcinoma.

Target:
TNBC

A.I.A.N. - Modena

Neoplasie della mammella

Anno: 2012

Anno: 2013

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