Neoplasie della mammella
Anno: 1996
-
Riferimento:Br J Cancer. 1996 Nov;74(9):1466-8.Azione della melatonina:Combination with Tamoxifene plus Melatonin (20 mg day) may have some benefit in untreatable metastatic solid tumour patients.Target:Melatonin/tamoxifen
-
Titolo: Melatonin in human breast cancer tissue: association with nuclear grade and estrogen receptor statusRiferimento:Lab Invest. 1996 Oct;75(4):557-61.Azione della melatonina:ExogenousMLT may influence nuclear grade and/or estrogen receptor activity in breast cancer patients.Target:Nuclear grade/melatonin
-
Riferimento:J Pineal Res. 1996 Apr;20(3):173.Azione della melatonina:No abstract available.Target:No abstract available.
-
Riferimento:J Toxicol Environ Health. 1996 Jun 7;48(2):169-85.Azione della melatonina:50-Hz, 100-mG MF significantly decreases circulating melatonin but is not associated with a development of DMBA-induced mammary tumors.Target:Dimethylbenzanthracene (DMBA) Magnetic field (MF)
Anno: 1997
-
Riferimento:J Pineal Res. 1997 Nov;23(4):169-75.Azione della melatonina:Melatonin [(10(-9) M or10(-10) M) for 2 and 5 days] induced very slight alterations in microtubule organization of all cell lines studied.Target:Cytoskeleton.
-
Riferimento:Pharmacol Toxicol. 1997 Dec;81(6):265-70.Azione della melatonina:Seasonal variation in the development and growth of DMBA-induced breast cancer as the seasonal variation in pineal melatonin production.Target:Circannual rhythms.
-
Riferimento:Wien Klin Wochenschr. 1997 Oct 3;109(18):722-9. Review. German.Azione della melatonina:Yet unknown chemical structure are capable of inhibiting in vitro cell lines resistant to melatonin.Target:Progressive decline of pineal melatonin secretion.
-
Riferimento:J Pineal Res. 1997 Sep;23(2):53-8.Azione della melatonina:Decreased pineal melatonin secretion in breast cancer patients as well as an inverse relationship with tumor-size.Target:6-sulphatoxymelatonin (aMT6s)
-
Riferimento:Cancer Res. 1997 May 15;57(10):1909-14.Azione della melatonina:10 microM L-buthionine-[S,R]-sulfoximine(L-BSO) blocks the oncostatic action of 1nM melatonin, glutathione(1microM) is required for melatonin action.Target:Glutathione.
-
Riferimento:J Pineal Res. 1997 May;22(4):184-202. Review.Azione della melatonina:Melatonin could indeed be considered a physiological anticancer substance.Target:Antioxidative functions, indirect immunostimulatory effects.