Neoplasie della mammella
Anno: 1996
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Riferimento:Environ Health Perspect. 1996 Mar;104 Suppl 1:135-40. Review.Azione della melatonina:Light and EMF effects on melatonin; melatonin effects on breast cancer.Target:Light at night (LAN),ele-ctromagnetic fields(EMF)
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Riferimento:Int J Occup Environ Health. 1996 Jan;2(1):37-47.Azione della melatonina:Associations between EMF exposure, breast cancer and modifications of melatonin secretion could be a biologic signal of these effects.Target:50/60-Hz electric and magnetic fields (EMF)
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Riferimento:Bioelectromagnetics. 1996;17(5):396-405.Azione della melatonina:Effects of light and electromagnetic fields (EMFs) could have implications for long-term risk of breast cancer, peak levels may be consistent with those thought to suppress melatonin.Target:Light and electromagnetic fields (EMFs)
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Titolo: Modulation of the length of the cell cycle time of MCF-7 human breast cancer cells by melatoninRiferimento:Life Sci. 1996;58(9):811-6.Azione della melatonina:Melatonin,(10(-9)M) added to the culture medium, increased the duration of the cell cycle of human breast cancer cells, delaying the entry into mitosis.Target:Melatonin inhibitory effect
Anno: 1997
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Riferimento:J Pineal Res. 1997 May;22(4):184-202. Review.Azione della melatonina:Melatonin could indeed be considered a physiological anticancer substance.Target:Antioxidative functions, indirect immunostimulatory effects.
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Riferimento:Support Care Cancer. 1997 Mar;5(2):126-9.Azione della melatonina:Concomitant administration of MLT during chemo-therapy may prevent some chemotherapy-induced side-effects,Target:Influence of MLT on chemotherapy toxicity.
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Riferimento:Bioelectromagnetics. 1997;18(8):555-62.Azione della melatonina:Melatonin (10(-9) M) and tamoxifen (10(-7) M) may act through different biological pathways to down-regulate cell growth.Target:EMF (1.2 microT, 60 Hz).
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Riferimento:Breast Cancer Res Treat. 1997 Jan;42(1):15-22.Azione della melatonina:Breast cancer women had a reversal of the normal seasonal pattern of melatonin secretion.Target:Seasonal variation.
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Riferimento:Cancer Lett. 1997 Jan 1;111(1-2):59-66.Azione della melatonina:Combined therapy of melatonin (200 microg/day, p.o.) and tamoxifen is highly promising in the prophylaxis of breast carcinogenesis in humans.Target:Melatonin/tamoxifen
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Riferimento:J Pineal Res. 1997 Nov;23(4):169-75.Azione della melatonina:Melatonin [(10(-9) M or10(-10) M) for 2 and 5 days] induced very slight alterations in microtubule organization of all cell lines studied.Target:Cytoskeleton.