ABSTRACT
Prostate cancer (PC) is the second most common cancer in men worldwide. Its prevention and treatment remain a challenge to clinicians. Here we review the relationship of vitamins to PC risk. Many vitamins and related chemicals, including vitamin A, retinoids, several B vitamins, vitamin C, vitamin D and vitamin E have shown their anti-cancer activities as anti-oxidants, activators of transcription factors or factors influencing epigenetic events. Although laboratory tests including the use of animal models showed these vitamins may have anti-PC properties, whether they can effectively prevent the development and/or progression of PC in humans remains to be intensively studied subjects. This review will provide up-to-date information regarding the recent outcomes of laboratory, epidemiology and/or clinical trials on the effects of vitamins on PC prevention and/or treatment.
Vitamins and prostate cancer risk
Riferimento:
Molecules. 2010 Mar 12;15(3):1762-83. Review.
Autori:
Donkena KV, Karnes RJ, Young CY.
Fonte:
Molecules. 2010 Mar 12;15(3):1762-83. Review.
Anno:
2010
Azione:
Molte vitamine e prodotti chimici correlati, tra cui la vitamina A, retinoidi, diverse vitamine del gruppo B, vitamina C, vitamina D e vitamina E hanno dimostrato la loro attività anti-cancro, anti-ossidante, attivatore dei fattori di trascrizione o di fattori che influenzano gli eventi epigenetici nel cancro della prostata (PC).
Target:
Retinoidi/cancro della prostata.
Sostanze: