Riferimento:
Tex Heart Inst J. 2012;39(1):76-8.
Autori:
Eapen DJ, Clements S Jr, Block P, Sperling L.
Fonte:
Tex Heart Inst J. 2012;39(1):76-8.
Anno:
2012
Azione:
In un tumore carcinoide metastatico gastrointestinale, nonostante terapia con octreotide, nitrati e sul blocco dei canali del calcio, il livello di acido acetico 5-idrossi-indolo urinario è aumentato, con progressiva vasospasmo coronarico.
Target:
Octreotide-nitrati-blocco canali-Ca/tumore carcinoide metastatico gastrointestinale.
ABSTRACT
Herein, we report a case of progressive coronary vasospasm in a 70-year-old man who had a long-standing history of metastatic gastrointestinal carcinoid tumor. Despite octreotide, nitrate, and calcium channel-blocker therapy, the patient's urinary 5-hydroxy-indole acetic acid level increased, coinciding with an increased frequency of flushing episodes with chest discomfort. In the cardiac catheterization laboratory, we captured an episode that was associated with diffuse right coronary artery spasm, ST-segment elevation, and intense symptoms. We attribute the patient's coronary vasospasm to his metastatic carcinoid disease.
Sostanze: