Neoplasie della mammella
Anno: 2007
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Riferimento:Breast Cancer Res Treat. 2007 Jul;103(3):331-41.Azione della melatonina:Melatonin and estrogen in BCF predicted growth inhibition and stimulation. Biological monitoring of BCF may help identify women with GCBD at greatest risk for breast cancer development.Target:(GCBD) Gross cystic breast disease Breast cyst fluid (BCF).
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Riferimento:Crit Rev Oncog. 2007 Dec;13(4):303-28Azione della melatonina:Both human epidemiological and experimental studies on animals have documented that a potential negative consequence of chronodisruption and nocturnal melatonin inhibition is cancer initiation and growth (breast, prostate, endometrial, and colorectal).Target:LAN
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Riferimento:Cell Cycle. 2007 Jun 1;6(11):1329-31.Azione della melatonina:Here we speculate on the molecular pathways that may couple the circadian machinery to breast cancer.Target:Circadian clock
Anno: 2008
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Riferimento:Cancer Lett. 2008 Sep 18;268(2):272-7.Azione della melatonina:Melatonin inhibition of telomerase activity supports a possible role in treatment of estrogen-dependent tumors.Target:HumanTelomerase ReverSeTranscriptase (hTERT)
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Riferimento:Aviat Space Environ Med. 2007 Apr;78(4 Suppl):A26-37.
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Riferimento:Integr Cancer Ther. 2008 Sep;7(3):189-203.Azione della melatonina:Melatonin's oncostatic actions include the direct augmentation of natural killer (NK) cell activity, which increases immunosurveillance, stimulation of cytokine production and protection on hematopoietic precursors from the toxic effect of anticancer chemotherapeutic drugs.Target:Immunomodulation, hematopoiesis, and antioxidative processes.
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Riferimento:Carcinogenesis. 2008 Jun;29(6):1244-8.Azione della melatonina:Melatonin inhibition of telomerase activity supports a possible role in treatment of estrogen-dependent tumors.Target:HumanTelomerase ReverseTranscriptase (hTERT)
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Riferimento:J Natl Cancer Inst. 2008 Jun 18;100(12):898-905.Azione della melatonina:Statistically significant inverse association between melatonin levels, as measured in overnight morning urine, and invasive breast cancer risk in postmeno pausal women.Target:6-sulfatoxymelatonin.
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Riferimento:Carcinogenesis. 2008 Jun;29(6):1244-8.Azione della melatonina:Sleep duration may influence breast cancer risk, possibly via its effect on melatonin levels.Target:6-sulfatoxymelatonin.
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Riferimento:Cancer Epidemiol Biomarkers Prev. 2008 Jun;17(6):1418-23.Azione della melatonina:Exposure to light at night has implications for the risk of breast cancer in postmenopausal women.Target:6-sulfatoxymelatonin.