Observational study on 55 patients affected lymphoma, treated with the Di Bella Method (DBM). The 1, 3 and 5-year survival rates are reported, together with any signs of toxicity. The patients were able to continue the treatment at home, carrying out their normal activities without problems.

Importance of taking into account endogenous rhythmicity and limiting melatonin administration to the subjective night (2 mg/kg BW/day) in order to restrict melanoma progression.

Melatonin is considered a promising antitumor agent, promoting apoptosis in tumor cells and contrasting it in normal cells.

Melatonin, 10(-5) M/10(-3) M, does not interfere with the cytotoxic effect of cytarabine, daunorubicin and etoposide in leukemia cells.

Magnetic field exposure, cause of leukemia and other cancers, was not associated with a significant reduction in serum melatonin.

50-60 Hz magnetic fields as "possibly carcinogenic to humans" because of the "limited evidence" of carcinogenicity of residential exposure relatively to childhood leukemia, perhaps for subtle differences in the timing of melatonin release.

Supplementation by exogenous melatonin (20 and 40 mg/kg body weight) significantly reduces MTX-induced small intestinal damage.

Melatonin PGE1 and TXA2 are important in the regulation of fibrosis and defective T suppressor cell function.

MLT inhibition increasing the risk of melanoma by increasing circulating oestrogen levels. No studies reporting on the relationship between melanoma and number of sleeping hours, etc.

Night work may increase cancer risk at several sites among men, possibly via suppression of melatonin release.