Leucemie Linfomi Mielomi

Leucemie Linfomi Mielomi

Prevention of immune dysfunction and vitamin E loss by dehydroepiandrosterone and melatonin supplementation during murine retrovirus infection

Immunology. 1999 Feb;96(2):291-7.
Zhang Z, Araghi-Niknam M, Liang B, Inserra P, Ardestani SK, Jiang S, Chow S, Watson RR.
Dhea and Mlt simultaneously reduced hepatic lipid peroxidation and prevent vitamin E loss.
Prevent (Th1, Th2) cyto-kine dysregulation.

A phase II study of neuroimmunotherapy with subcutaneous low-dose IL-2 plus the pineal hormone melatonin in untreatable advanced hematologic malignancies

Anticancer Res. 2000 May-Jun;20(3B):2103-5.
Lissoni P, Bolis S, Brivio F, Fumagalli L.
The concomitant administration of low-dose IL-2 plus Mlt may prolong the survival time in untreatable advanced hematologic malignancies.
Low doses of Interleukin-2 (IL-2).

The influence of long-term exposure of mice to randomly varied power frequency magnetic fields on their nocturnal melatonin secretion patterns

Environ Res. 2001 Feb;85(2):115-21.
de Bruyn L, de Jager L, Kuyl JM.
Long-term and continuous exposure to simulate powerline magnetic fields did not result in a decreased nocturnal melatonin secretion in mice.
Average of 2.75 microT magnetic fields.

Effects of melatonin on doxorubicin cytotoxicity in sensitive and pleiotropically resistant tumor cells

J Pineal Res. 2001 Oct;31(3):206-13.
Granzotto M, Rapozzi V, Decorti G, Giraldi T.
In the concentration range 10-2000 pg/ml causes an inhibition of the growth of the human cell lines is not clearly dose-dependent and less than 25% when significant. 200-1000 pg/ml melatonin cause a significant sensitization to doxorubicin.
Might inhibit P-glycopro tein-mediated doxorubicin efflux from the cells.


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